Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that act on muscle cells’ autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans, it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.
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